The tadalafil, prescription treatment better known under the trade name Cialis was originally developed for the treatment of erectile dysfunction (also called male impotence). Since 2013 it is now approved for the treatment of benign prostatic hyperplasia syndrome.

Indeed clinical studies have shown a significant decrease in the symptoms of benign prostatic hyperplasia when taking Cialis, although to date the explanatory factors are not perfectly known.

Statistics have long shown some correlation between urinary disorders of benign prostatic hyperplasia, those of erectile dysfunction or ejaculatory disorders.

Between the ages of 40 and 70, an average of 60% of men suffers from urinary disorders caused by benign prostatic hyperplasia, and over 50% suffer from erectile dysfunction to varying degrees.

Faced with these disorders known by millions of men, treatments exist and are implemented. This is particularly the case of Cialis 5 mg, a daily treatment in doses of 5 or 2.5 mg of Tadalafil, whose effectiveness has been significant in patients suffering from prostate problems that we detail below.

What is benign prostatic hyperplasia syndrome?

The syndrome of benign prostatic hyperplasia manifests itself at two different levels. On the one hand, it is manifested by invisible manifestations such as pain when urinating (painful urination) and, on the other hand, by visible and objective manifestations such as obstruction of the urinary flow through the prostate.

Most often the diagnosis of the doctor indicates abnormalities in the high and low region of the urinary system (kidney and urethra) and changes in the prostate including a widening of the latter which will create pressure on the urethra and generate various urinary symptoms and problems:

  • Need to go to urinate frequently or urgently
  • Stop or abbreviated urination
  • Need to push during urination
  • Urine flow reduced
  • Incomplete emptying of the bladder
  • Need to go to urinate regularly during the night

Benign prostatic hyperplasia can lead to significant complications. Therefore, evaluation by a doctor is recommended in all cases.

How does Cialis work for benign prostate syndrome?

Tadalafil, the active ingredient contained in Cialis, prevents the action of the enzyme phosphodiesterase 5 (PDE-5) to degrade specific endogenous substances, which provide, in particular, a muscle relaxant in the area of the urinary tract.

As a result, the neck of the bladder opens more strongly and emptying the bladder is facilitated. Scientific studies have shown that urinary discomfort (feeling of bladder empty, pain at the time of urination) due to the syndrome of benign prostatic hyperplasia was significantly moderate when taking Cialis.

It is this same muscle relaxation that this time, in the penis itself, allows an increased blood flow to the penis and thus makes it more conducive to erection in case of sexual stimulation.

Possible side effects

Patients taking Cialis may experience some of the following side effects: hot flushes, headache, or redness on the upper body. Other common side effects have also been reported such as nausea, dizziness, mild diarrhea, or nasal congestion. Occasionally, impaired color vision (tinged vision) may also occur when taking a Cialis treatment.

Less common side effects such as eye pain, hypotension, conjunctivitis, increased blood pressure, increased tearing, increased heart rate, palpitations, tremors, increased levels of certain enzymes Hepatic changes in the blood, increased sensitivity to light, nosebleeds, rash, drowsiness, or muscle pain may have occurred while taking the active ingredient Tadalafil.

In rare cases, a temporary increase in intraocular pressure, anxiety disorders, tinnitus, hypersensitivity, or priapism (erection lasting more than 2 hours) occurs.

Drugs interactions

Interactions may occur with concomitant use of Cialis with other drugs. These are in particular medicines:

  • Antifungals (eg Ketoconazole, Erythromycin, Itraconazole)
  • Active agents such as Ritonavir (anti-HIV)
  • Cimetidine (antihistamine to cushion the production of gastric juice)

These drugs can not only affect the patient’s liver metabolism, but also significantly increase the effect of the active ingredient contained in Cialis, Tadalafil, and in this case give rise to more frequent side effects and also more strong.

Similarly, vasodilators (Nitro-base) or alpha-sympatholytics (alpha-adrenergic antagonists) may interact with Cialis.

This may result in clotting disorders, a sharp drop in blood pressure, or a large increase in heart rate.

Finally, it is strongly advised to avoid associating tadalafil with grapefruit juice, because it prevents the decomposition and assimilation of tadalafil by the body.

Categories: USA